A painter and master printmaker, Antreasian was born in Indianapolis and graduated from the John Herron Art Institute. He was an instructor at the school when he painted Sign of the Times, which won first prize in the L.S. Ayres & Co. 75th anniversary contest. The painting shows the Union Title Building at the southeast corner of Washington and Pennsylvania where several local artists, including Antreasian, had established studios. In this image, Antreasian tries to maintain a balance between realism and abstraction. The "One Way" arrow and "Vote Now" pennant reflect the artist's interest in the random, evocative signs of our civilization. The forms also suggest the hypnotic allure of marks, such as the "S" and "13" in the foreground, which have no literal translation.